Quantitative analysis of nicotine and its metabolites, such as cotinine, in biological samples like blood, urine, or saliva, yields measurable values within specific parameters. These parameters, often expressed as numerical intervals, reflect the concentration of these substances. For example, a saliva test might indicate cotinine levels between 0 and 10 ng/mL for non-smokers, and significantly higher values for tobacco users.
Understanding these quantitative parameters is crucial for various applications. In clinical settings, these values help determine the extent of tobacco exposure, monitor smoking cessation progress, and assess potential health risks. Furthermore, such data plays a vital role in research studies investigating the effects of nicotine on the body and in epidemiological surveys tracking tobacco use prevalence. Historically, advancements in analytical techniques have enabled more precise and reliable measurements, contributing significantly to our understanding of nicotine’s impact on public health.