This blood analysis helps evaluate the function and quantity of a specific protein crucial for regulating the complement system, a part of the immune system. Low levels or impaired function can lead to uncontrolled activation of this system, causing swelling in various body parts. For example, a deficiency can contribute to hereditary angioedema (HAE), a condition characterized by recurrent episodes of swelling.
Quantifying and assessing this protein’s activity is essential for diagnosing and managing conditions like HAE. Accurate measurement allows healthcare professionals to distinguish HAE from other conditions with similar symptoms, enabling prompt and appropriate treatment. Historically, diagnosing HAE was challenging due to limited understanding of its underlying mechanisms. The development of this assay represented a significant advance in diagnosing and managing this often debilitating condition.
