Insulin-like growth factor 1 Long R3 (IGF-1 LR3) is a synthetic analog of human IGF-1, a hormone crucial for growth and development. This variant has a modified structure, increasing its half-life and potency compared to naturally occurring IGF-1. This characteristic leads to prolonged stimulation of cell growth and proliferation in various tissues, including muscle.
Enhanced muscle protein synthesis and reduced protein breakdown are key outcomes associated with increased IGF-1 activity. These processes are fundamental for achieving muscle hypertrophy (growth) and improving overall body composition. Historically, research on IGF-1 has explored its role in treating growth disorders. The potential for performance enhancement has spurred further investigation into its effects on muscle development and recovery in athletes and fitness enthusiasts. However, understanding the potential risks and ethical implications is crucial.