Understanding the concentration of cortisol in saliva samples provides valuable insights into the body’s adrenal function. This analysis involves measuring cortisol levels at different times of the day to assess the diurnal rhythm, which typically shows a peak in the morning and a gradual decline throughout the day. For example, elevated evening levels may indicate chronic stress or specific adrenal disorders.
This assessment offers a non-invasive and convenient method for evaluating adrenal activity. Historically, blood serum was the primary medium for cortisol measurement. Salivary testing offers a less stressful alternative, particularly beneficial for children or individuals with needle phobias, while offering a reliable correlation with free cortisol levels in serum. Accurate adrenal function assessment plays a crucial role in diagnosing and managing various conditions, including Cushing’s syndrome, Addison’s disease, and stress-related disorders.
